Volume 2 Issue 2
Serological and clinical findings in dogs seropositive for Anaplasma phagocytophilum and Borrelia burgdorferi
Katharina Möhler, Michael Leschnik, Claus Vogl, Dieter Barutzki, Anja Joachim*
Anaplasma phagocytophilum and Borrelia burgdorferi sensu lato are two major tick-borne pathogens of dogs. To gain insight into the clinical findings and possible correlations between clinical signs and seropositivity, a cohort of 254 dogs of different breeds, age, and sex was investigated for serum antibody titers against these pathogens and hematological as well as clinical parameters, focusing on lameness and neurological disorders. Overall, 64.2% of the dogs were seropositive for Anaplasma and 61.0% for Borrelia, including 40.2% positive for both agents, and a statistically significant association between both pathogens.
Safety of Vaccination with an Inactivated or Modified Live Viral Reproductive Vaccine When Compared to Sterile Saline in Beef Cows
George A. Perry*, Erin L. Larimore, Melissa R. Crosswhite, Brian W. Neville, Victor S. Cortese, Russell F. Dalye, Gerald Stokka, John. C. Rodgers, Jon T. Seeger, and Carl R. Dahlen
A two year study involving nine herds of well-vaccinated cows and heifers (n=1436) was conducted to evaluate whether a pre-breeding inactivated or MLV reproductive vaccine administered per label instructions had negative impacts on conception rates or calving distribution compared to a non-vaccinated control (saline) group. Within herd, cows were blocked by parity and calving date and randomly assigned to receive one of the three treatments: 1) MLV, 2) Inactivated) or 3) saline. No pre-vaccination screening for prior response to vaccination was performed and no monitoring for reproductive diseases occurred during the study. All females were synchronized with the 7-day CO-Synch + CIDR protocol and artificial inseminated (AI) at the appropriate time after CIDR removal (cows 60 to 66 hrs; heifers 52 to 56 hrs).